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4.4 Interactions between cartilage and synovium 4.4.1 Interplay between cytokines released by chondrocytes and synovial cells When cartilage is damaged, chondrocytes release proteoglycan fragments, type II collagen fragments, and diverse injury-associated factors that synovial cell surface pattern recognition receptors (PRRs) can detect, prompting synovial hyperplasia and proinflammatory cytokine secretion (139) Sharps Bin:Black https://lookaside.fbsbx.com/lookaside/crawler/instagram/DVqndk3DMUj/0/image.jpg Skin Type: Sensitive Crème Éclaircissante Glutathion VEERA

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