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While the Shc binding to TrkB couples the activated receptor to the Ras/extracellular signal-regulated kinase (ERK) and the phosphatidylinositol 3-kinase (PI3K) signaling pathways, the PLC-γ interaction is responsible for the formation of the second messengers inositol triphosphate (IP 3 ) and diacylglycerol, Ca 2+ release from intracellular Ca 2+ stores and activation of protein kinase C (Ernfors and Bramham, 2003) Fragrance:Lavender https://gcs.buymed.com/thuocsi-live/images/202493431addcfd3380876971ff8127e Infinity Skincare MyVitamin B12™ ProClinical – Purity Products

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