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Keywords: exocytosis, RAB GTPases, Spitzenkörper, type V myosin, exocyst Graphical abstract Highlights • RAB11 governs the biogenesis and tip-directed transport of secretory vesicles (SVs) • Within the tip, MyoE (myosin V) concentrates SVs at the Spitzenkörper (SPK) • Sec4 and MyoE govern transport of SVs from the SPK to the plasma membrane • Sec4 and MyoE also cooperate to recruit the exocyst to SVs Biological morphology
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