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Improving glutathione production by engineered Pichia pastoris: strain construction and optimal precursor feeding | Applied Microbiology and Biotechnology | Springer Nature Link

In cell-based studies, GHK-Cu has been reported to stimulate production of collagen and other components of the extracellular matrix, the scaffolding that gives skin its structure (1)(2)

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For example, when EndoMT is induced in human lung endothelial cells, there is an increase in short-chain acylcarnitines, a decrease in glycolytic and TCA cycle metabolites, decreased CPT1A expression, decreased fatty acid metabolism, and reduced levels of acetyl-CoA