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Liposomal CoQ10: Solving the Statin-Induced Depletion Gap
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Its reduced expression was associated with decreased levels of the histone marks H3K4me3 and H3k27ac at the Nr1i3 promoter, both indicators of active transcription, consistent with the known role of HNF4α in recruiting histone acetyl transferases to promote a transcriptional permissive chromatin environment (74)
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