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Comparison of blood glucose from nonfasted Nrf2-null and wild-type mice fed on a regular chow diet have been reported to be closely similar, as were overnight-fasted blood glucose levels [144, 226, 227], and intraperitoneal glucose tolerance tests of fasted Nrf2 −/− and Nrf2 +/+ mice on a regular chow diet revealed similar levels of glucose disposal in the two genotypes
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In the following sections, we will discuss the nephroprotective effects and the underlying protective mechanisms of ALA in a variety of animal models of kidney injury, as indicated in Figure 1
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