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discovered that Tα1 inhibited the transcription of MMP2 by inhibiting phosphorylation of STAT3, resulting in a decrease in MMP2 protein expression and inhibiting the migration and invasion of NSCLC cells with programmed cell death ligand 1 (PD-L1) high-expressing, which suggests that Tα1 may inhibit the STAT3-MMP2 signaling pathway by stimulating PD-L1 (46)
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