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Additionally, 1,8-diMQ and 5-amino-1MQ showed little inhibition of COMT at maximal tested concentrations of 200 μM (20% inhibition) and 600 μM (10% inhibition), respectively, although no clear trend of concentration-dependent inhibition was observed
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In neuroblastoma (N2a), curcumin induced NEP promoter demethylation and restored its inhibition of the Akt/NF-κB pathway (Deng et al., 2014)
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