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A base substitution at the splice acceptor site of intron 5 of the COL1A2 gene activates a cryptic splice site within exon 6 and generates abnormal type I procollagen in a patient with Ehlers-Danlos syndrome type VII
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It helps to restore the integrity of the tight junctions between intestinal cells, effectively "sealing the leaks." By healing the gut, we often see a dramatic reduction in systemic inflammation and a resolution of the symptoms it causes
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