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Work published in Biologicals by Qian and colleagues in an industrial CHO cell line found that LR3 improved protein productivity and also altered product quality: the recombinant Fc-fusion protein had higher sialic acid content and a lower percentage of asialylated N-linked glycans, an effect the authors traced to decreased Neu2 sialidase expression in response to LR3
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Peptide therapies are moving closer to legal compounding after an FDA advisory committee backed 6 controversial peptides, including BPC-157 and TB-500
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