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Patients with chronic pancreatitis have lower levels of glutathione, cysteine, and glycine.[ref] Increasing cysteine levels with NAC is protective against pancreatic damage.[ref] Schizophrenia: Several research studies show that people with schizophrenia have lower glutathione levels in certain regions of the brain.[ref] In aging: The studies on glutathione in aging show that there is usually a general decrease in serum glutathione levels as we age

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Black and Asian individuals have a higher risk of developing hyperhomocysteinemia compared with individuals of other ethnicities