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Insulin-like growth factor 1 (IGF-1): a growth hormone.Mol Pathol 2001
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Moreover, the adhesion and motility of tumor cells are partly mediated by epithelial-mesenchymal transition (EMT), a process in which cuboidal epithelial cells undergo morphological and biological changes to transition into a mesenchymal phenotype with an elongated and spindle-like shape, thereby allowing the cancer cells to migrate and increasing their metastatic potential [67]
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