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Frontiers | Spotlight on Ferroptosis: Iron-Dependent Cell Death in Alzheimer's Disease

In molecular gerontology, cellular cytogenetics, and aging research, it represents a primary reference standard for studying mechanisms that bypass the Hayflick limit in somatic cell lines, reactivate the catalytic telomerase complex, and modulate gene accessibility via heterochromatin relaxation: Induction of Telomerase (hTERT) Expression & Catalytic Activity: Stimulates the transcription of human telomerase reverse transcriptase ( hTERT ), restoring telomerase enzymatic activity and facilitating telomere maintenance or elongation in primary human somatic fibroblast cultures in vitro

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NSAIDs work by inhibiting the enzyme cyclooxygenase (COX), which reduces the production of prostaglandins—chemicals responsible for pain, inflammation, and fever