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This pathway activation enables: Enhanced endothelial cell proliferation and migration Improved microvessel formation in tissue models Increased nutrient and oxygen delivery to follicular structures Support for anagen phase maintenance in hair follicle cycles Studies in hair follicle organ culture showed that picomolar to nanomolar concentrations of AHK-Cu stimulated VEGF secretion, correlating with improved follicle elongation and dermal papilla cell viability
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