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[10] The unpredictability of oral bioavailability in different people is also a reason for a medication to be administered IV, as with furosemide

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At the end of the reperfusion period, all animals were euthanized by exsanguination under deep anesthesia induced with ketamine (45 mg/kg) and xylazine (5 mg/kg), administered intramuscularly into the forelimb muscles to ensure complete loss of pain and reflexes