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2.2.1 Lipoprotein retention and oxidative modification After low-density lipoprotein (LDL) crosses the damaged endothelium into the arterial intima, it is retained by the extracellular matrix and undergoes oxidative modification to form oxidized LDL (OxLDL)
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The EFSA notes, “The inherent uncertainty of this [factorial] approach is reflected in the wide range of cobalamin intake calculated to compensate for estimated daily losses, depending on the assumptions taken (EFSA, 2015).” Appendix D
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