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Inhibiting SREBPs is another defensive reaction to intracellular cholesterol accumulation and results in the decreased expression of genes that regulate cholesterol synthesis (e.g., HMGCR) and uptake (e.g., LDLR) (Luo et al., 2020)
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A GHK-Cu facial cream reduced visible signs of aging after 12 weeks of application to the facial skin of 71 women with mild to advanced signs of photoaging
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