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Additionally, NFE2L2 (also known as NRF2), a key regulator of oxidative stress, appeared activated in high-GSH cells due to increased redox pressure (64)
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Curcumin-supplemented KI mice showed reduced mHTT aggregation and upregulated mRNA expression of striatal DARPP-32 and dopamine receptor D1, which were accompanied by behavioral recovery, particularly in rearing deficits (Hickey et al., 2012)
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