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doi: 10.1016/j.canlet.2019.09.015 72 HuLXuXLiQChenXYuanXQiuSet al

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Moreover, the phase II studies of APR-246 in MDS/AML reported the occurrence of neurological adverse events in over a third of patients treated with APR-246

Reduced Glutathione (GSH) can react with Dinitrobenzoic acid (DNTB) to form a yellow complex which can be detected by colorimetric assay at 405 nm and calculate the reduced GSH content indirectly.