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These genes code for a group of cytoprotective and antioxidant proteins that include multiple components of the thioredoxin pathway, antioxidant enzymes, i.e., NADPH quinone oxidoreductase 1 (NQO1) and heme oxygenase 1 (HO-1), and numerous enzymes that regulate glutathione biosynthesis and utilization (80)
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Association between glutathione-S-transferase GSTP1 genotypes, GSTP1 over-expression, and outcome in epithelial ovarian cancer
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