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They reported significant improvements in sperm motility (24% to 35%) and sperm morphology (58% to 71%).9 Cinnoxicam, an anti-inflammatory agent, was observed to significantly improve the seminal parameters in grade 3 varicocele, but cessation of therapy led to decline to baseline values.10 Cavallini et al .,11 in a randomized prospective controlled study of 325 patients suffering from clinical or subclinical varicocele or idiopathic male infertility, compared the effects of combination therapy of carnitine (2 g per day) + L-acetyl carnitine (1 g per day) + cinnoxicam (30 mg suppository every 4 days) with carnitine (2 g per day) +L-acetyl carnitine (1 g per day) for a duration of 6 months

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