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miR-125a is frequently downregulated in several human cancer such as ovarian, non small-cell lung and gastric cancer and colorectal cancer (83–85) Moreover low expression of miR-125a is associated with increased tumor diameter, high Ki67 expression and poor overall survival of patients with gastric carcinoma (86) Additionally miR-125a deficiency enhances agiogenic processes through metabolic reprogramming of endothelial cells (87)
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