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In 1981 Flückiger et al observed that a sub-fraction of hemoglobin A 1 was carbamylated, and that the proportion of carbamylated hemoglobin was related to patient’s blood urea concentrations
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By analogy with the cysteine S -conjugate β-lyase reaction with the cysteine S -conjugate THT-A, we predict that a β-lyase reaction on 1-(2-amino-2-carboxyethyl)thiiranium will lead to elimination of thiirane, which may possibly be a bioactivation event
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