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known as paracetamol in most countries outside of the United States and Canada) is readily accessible and is an ingredient in more than 200 over-the-counter and prescription medications, either as a single agent or in combination with other pharmaceuticals

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Artesunate and dihydroartemisinin may ameliorate lung tissue inflammation through the HMGB1/TLR4/NF-κB pathway and alleviate lung injury induced by various factors, these compounds decrease inflammatory cell infiltration, immune cell (macrophages, neutrophils, eosinophils, and lymphocytes) counts, and inflammatory mediator (TNF-α, IL-1β, IL-6, IL-10, IL-12, and TGF-β) levels (Li et al., 2023