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Study Design: Validating Immune Synergy in Early Relapse MAJEStec-3 is a global, randomized, open-label Phase III trial designed to test the hypothesis of immune synergy between the CD38-targeting antibody Daratumumab and the BCMA x CD3 bispecific antibody Teclistamab
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In particular, it was found that NNMT is required for low SAM levels and H3K27me3 repressive state
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