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Expression of TLRs gives Müller cells phagocytic capacity, and they are critical for the maintenance of homeostasis, removal of neuronal debris and retinal reorganization and regeneration (Sakami et al., 2019)
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The reactive species oxidize the different types of amino acids present in the protein and result in the generation of the protein-protein cross linkage which further results in the denaturation, loss of protein functioning, loss of transport protein and receptor functioning, and loss of enzymatic activity
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