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In addition, astrocytes, which normally support neurons, become dysfunctional through a process called astrogliosis, which worsens glutamate imbalance and reduces neuronal support (Taylor et al., 2016), and genetic mutations—such as SOD1 (causing harmful protein accumulation), FUS (interfering with RNA handling), and TBK1 or OPTN (which impair the cell's waste disposal system known as autophagy
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Size:50 mg
After tipping off the supernatant, diluted serum samples were incubated for 2 h at RT
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