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IREs are found in the 5ꞌ UTRs of mRNAs of both α-synuclein [223,394,395] and amyloid precursor protein (APP) [221] (Fig
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Impaired Selenoprotein Biosynthesis and Lipid Peroxidation: Lessons from Selenocysteine Insertion Sequence (SECIS)-Binding Protein 2 (SBP2) Deficiency To further understand how impaired selenium metabolism promotes oxidative membrane damage, we next consider the biosynthetic system that supports selenoprotein production
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