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l-carnitine therapy in non-alcoholic steatohepatitis Carnitine metabolic disorders and novel clinical approaches: Mechanistic insights from deficiency management to liver and kidney disease treatment coenzima
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We found that loss of malonyl-CoA synthesis by pharmacologic ACC inhibition or liver-specific knockout of ACC1/2 (LDKO) increased acetyl-CoA and TCA cycle intermediate concentrations and stimulated oxidative metabolism and gluconeogenesis in a manner that required CPT-1 activation and pyruvate carboxylation
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Evolution of the human pygmy phenotype
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