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Moreover, ferritinophagy is mediated by nuclear receptor coactivator 4 (NCOA4), which can be inhibited by HIF-1a and endothelial cell (EC)-derived extracellular vesicles (Exos) (36)
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112,113 Moreover, given the multiplicity of 5-HT 2A receptor-expressing GABAergic interneurons on principal cells, eg, in the amygdala and hippocampus, 107 it seems likely that the effects of pharmacological treatments that either activate or inhibit 5-HT 2A receptors are overwhelmingly mediated by downstream effects of GABA neurotransmission
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